Ypercholesterolemia. Statins inhibit 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, an early
Ypercholesterolemia. Statins inhibit 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, an early and rate-limiting enzyme of cholesterol synthesis, thereby stopping the conversion of HMGCoA to mevalonate, and decreasing the levels of mevalonate…